What is Alli?
Alli is an OTC weight loss supplement and belongs to the lipase inhibitors category of fat loss medication. Alli is manufactured by gigantic GlaxoSmithKline multinational company and it’s currently the only OTC diet medication with FDA approval.
Tempted to give it a try?
Who’s Alli for?
Alli works best for obese people, who’ve tried dieting and exercising and had poor results. GSK does not recommend Alli for Individuals with a BMI under 28, as they won’t see substantial changes in weight and body composition.
How exactly does it work?
Alli works by incapacitate a fat-processing enzyme, called lipase. Since lipase is disabled, the absorption of fat by the body is significantly reduced. As fat can’t be processed and stored as fat tissue, it passes naturally through bowel movement.
It’s noteworthy, how Alli’s effectiveness largely depends on each individual’s commitment to consume less than 15gr of fat per meal. Larger portions of fat result in unpleasant and socially awkward treatment effects (see below).
Orlistat is the main ingredient in Alli which is capable of absorbing ¼ of the fat one consumes. Alli has then a two-fold function, it prohibits fat absorption and keeps calorie intake low, since 25% of fat is forbidden from being turned into energy.
What’s in it?
As it has been mentioned, Alli’s primary ingredient is Orlistat, with 60mg of Orlistat included in each Alli pill. This reduced amount of Orlistat is what allows Alli to be a safe and effective OTC weight loss supplement.
Orlistat is a comprehensively researched compound (over 50 studies up to 2005).
In a May 2012 study researching the effectiveness of Alli for weight loss, the researchers concluded that those treated with Alli before surgery had beneficial weight results.
Another study on Alli’s efficacy suggested:
“[S]ibutramine and Orlistat were effective in weight reduction, with Orlistat having a more favorable effect on lipid profile”.
On a similar vein, a 2011 Spanish study concluded:
“Sibutramine and Orlistat in combination with a hypocaloric diet and changes in lifestyle in obese adolescents achieve a short-term loss of weight greater than that achieved through the dietary-behavioral therapy alone”.
Yet again, another clinical trial on Orlistat found that:
“Orlistat is an effective and well-tolerated antiobesity drug, which can be employed as an adjunct to therapeutic lifestyle changes to achieve and maintain optimal weight.”
A study went further into investigating the effectiveness of Orlistat on obese adolescents, the results were also positive: “In combination with diet, exercise, and behavioral modification, Orlistat statistically significantly improved weight management in obese adolescents compared with placebo”.
Last, but not least and among numerous other medical reviews and trials, a study showed that
“Two-year treatment with Orlistat plus diet significantly promotes weight loss, lessens weight regain, and improves some obesity-related disease risk factors.”
Alli key advantages
As other weight loss medications, Alli is not a magic bullet. It can only be effective along the lines of a healthy diet and in the context of exercising.
In essence, Alli discourages you from eating more than 15gr of fat per meal— as this can lead to awkwardly embarrassing moments. In this manner it urges individuals to self-discipline themselves. This self-imposed restriction means that eventually the dieter will adapt to this new low-fat diet and make it part of his/her lifestyle. Hopefully, to the point where Alli won’t be necessary any longer.
What about Side effects and Downsides?
Those newly introduced to Alli are often discouraged from starting the Alli diet largely because of the side effects. The treatment effects of Alli, almost amount to a face-losing “penalty” with socially awkward incidents.
Surpassing the 15gr of fat threshold means:
- Flatulence with possible oily rectal spotting
- Urgent and Frequent bowel movements
- Diarrhea or loose stools
However if one sticks to the fat intake guidelines, Alli’s manufacturers claim that these treatment effects can be entirely eliminated.
Orlistat doesn’t distinguish between good and bad fat, as it’s the case with fat-soluble vitamins. For this reason and to avoid vitamin deficiency, it’s advisable to take multivitamins when Alli is administered.
As with all weight loss supplements, the benefits are counteracted by possible side effects. Whilst the effectiveness of Alli has been scientifically grounded with various clinical trials, one should consult their physician prior to taking Alli.
Should you choose to take Alli, you can buy it without prescription from your local chemist. On average, a 28-day pack costs about £49.95, it is also available for purchase directly from GlaxoSmithKline.
What slimming pill gives better results?
Considering the chemical based nature of the Alli slimming pills, there are lots of side effects involved into taking it.
UK market offers and incredible alternative to the Alli, which also works as a fat binder – but the difference between the Alli and Proactol is that the last one has virtually no side effects.
Proactol Plus is the fat binder with a numerous clinical trials and proven ability of block up to 27% of fat from digesting, which translates into appr. 295 calories cut from intake daily. It’s also a 100% certified slimming aid which is approved by MHRA – no other OTC slimming product presents such credibility on the market so far.
Since 2007, Proactol has helped thousands of slimmers to successfully achieve their desired weight goals that drew a lot of media attention in the UK and USA.
The product is delivered from the UK, and offers full 180-days money-back guarantee and 24/7 customer support.
Read Proactol Review To Discover More